SCHEMBL17033410

SCHEMBL17033410

c1ccc2c(c1)ccc1cc(-n3c4ccccc4c4cc5cc6c7ccccc7c7ccccc7n6c5cc43)ccc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
HSD17B10 Q99714 2/20 0.39
CYP1B1 Q16678 2/20 0.39
HIF1A Q16665 1/20 0.39
HPRT1 P00492 3/20 0.37
KDM4E B2RXH2 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CYP1A2 P05177 3/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
F2 P00734 1/20 0.33
F10 P00742 1/20 0.33
PRSS1 P07477 1/20 0.33
TDP1 Q9NUW8 2/20 0.33
CYP2A6 P11509 1/20 0.32
TSHR P16473 1/20 0.32
BACE1 P56817 1/20 0.32
CYP1A1 P04798 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17033507 0.96 HPRT1 (0.38) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL17033403 0.92 KDM4E (0.39) ALDH1A1KDM4EATML3MBTL1F2
SCHEMBL17033518 0.88 KDM4E (0.40) ALDH1A1KDM4EATML3MBTL1F2
SCHEMBL17033398 0.85 KDM4E (0.46) ALDH1A1HSD17B10KDM4EATML3MBTL1
SCHEMBL19769394 0.84 KDM4E (0.48) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL17228163 0.84 KDM4E (0.47) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL22926909 0.84 KDM4E (0.50) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL17033425 0.83 KDM4E (0.56) ALDH1A1KDM4EATML3MBTL1CYP1A2
SCHEMBL22250978 0.83 KDM4E (0.52) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL26705027 0.82 KDM4E (0.55) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015125986-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-08-27 WO disclosed