SCHEMBL17033463

SCHEMBL17033463

c1ccc(-c2cc(-c3ccccc3)nc(-c3cccc(-n4c5ccccc5c5cc6c(cc54)cc4c5ccccc5c5ccccc5n64)c3)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PDE10A Q9Y233 1/20 0.33
CYP19A1 P11511 1/20 0.33
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
KMT2A Q03164 5/20 0.32
MEN1 O00255 3/20 0.31
GAA P10253 1/20 0.31
GABRG2 P18507 1/20 0.30
GABRB3 P28472 1/20 0.30
GABRA5 P31644 1/20 0.30
GABRA3 P34903 1/20 0.30
RAB9A P51151 1/20 0.30
NPY5R Q15761 1/20 0.30
ACHE P22303 1/20 0.30
ALOX5 P09917 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17033615 0.97 KDM4E (0.37) KDM4EATML3MBTL1PDE10ACYP19A1
SCHEMBL16066168 0.93 KDM4E (0.38) KDM4EATML3MBTL1PDE10ACYP19A1
SCHEMBL16067237 0.91 KDM4E (0.36) KDM4EATML3MBTL1PDE10ACYP19A1
SCHEMBL16066444 0.91 KDM4E (0.36) KDM4EATML3MBTL1PDE10ACYP19A1
SCHEMBL16066989 0.90 KDM4E (0.37) KDM4EATML3MBTL1PDE10ACYP19A1
SCHEMBL17033467 0.90 KDM4E (0.39) KDM4EATML3MBTL1PDE10ATSHR
SCHEMBL17033469 0.89 ATM (0.45) KDM4EATML3MBTL1PDE10ATSHR
SCHEMBL22595915 0.88 ATM (0.46) KDM4EATML3MBTL1PDE10ACYP19A1
SCHEMBL17033382 0.88 KDM4E (0.37) KDM4EATML3MBTL1PDE10ACYP19A1
SCHEMBL19367171 0.87 KDM4E (0.50) KDM4EATML3MBTL1PDE10ACYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015125986-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-08-27 WO disclosed