SCHEMBL17033481

SCHEMBL17033481

c1cncc(-c2ccc(-c3cc(-n4c5ccccc5c5ccc6c(nc7c8ccccc8c8ccccc8n67)c54)cc(-c4ccc(-c5cccnc5)cc4)n3)cc2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.39
CYP19A1 P11511 3/20 0.38
CYP11B1 P15538 4/20 0.34
MAPT P10636 1/20 0.34
CYP11B2 P19099 4/20 0.33
CYP17A1 P05093 1/20 0.33
PDE2A O00408 3/20 0.32
PDE5A O76074 3/20 0.32
PDE11A Q9HCR9 3/20 0.32
PDE10A Q9Y233 3/20 0.32
PDE4A P27815 1/20 0.32
CYP2C9 P11712 3/20 0.32
METAP2 P50579 1/20 0.31
KDR P35968 1/20 0.31
TEK Q02763 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
HSD17B1 P14061 1/20 0.31
CYP2B6 P20813 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17033690 0.87 MAPT (0.41) CYP19A1CYP11B1MAPTCYP11B2CYP17A1
SCHEMBL17033897 0.87 CYP19A1 (0.40) DHODHCYP19A1CYP11B1MAPTPDE10A
SCHEMBL17033748 0.86 DHODH (0.41) DHODHCYP19A1CYP11B1MAPTCYP11B2
SCHEMBL16066194 0.85 DHODH (0.43) DHODHCYP19A1CYP11B1MAPTCYP11B2
SCHEMBL16066776 0.84 DHODH (0.41) DHODHCYP19A1MAPTCYP11B2PDE10A
SCHEMBL17033647 0.83 DHODH (0.40) DHODHCYP19A1CYP11B1MAPTCYP11B2
SCHEMBL16066500 0.83 DHODH (0.41) DHODHCYP19A1MAPTCYP11B2PDE10A
SCHEMBL17033718 0.82 CHRNB4 (0.36) CYP11B1MAPTCYP11B2
SCHEMBL17033679 0.82 DHODH (0.41) DHODHCYP19A1CYP11B1MAPTCYP11B2
SCHEMBL17033676 0.81 KDM4E (0.34) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015125986-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-08-27 WO disclosed