SCHEMBL17033484

SCHEMBL17033484

c1cc(-c2ccncc2)nc(-n2c3ccccc3c3cc4c(cc32)cc2c3ccccc3c3ccccc3n42)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MKNK1 Q9BUB5 1/20 0.37
MKNK2 Q9HBH9 1/20 0.37
MAPK14 Q16539 2/20 0.33
CDK5 Q00535 1/20 0.33
CDK5R1 Q15078 1/20 0.33
PRKCH P24723 1/20 0.32
PRKCE Q02156 1/20 0.32
CYP1A2 P05177 2/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2D6 P10635 2/20 0.32
CYP2C9 P11712 2/20 0.32
CYP2C19 P33261 2/20 0.32
NPC1 O15118 1/20 0.32
AR P10275 1/20 0.32
RAB9A P51151 1/20 0.32
NPY5R Q15761 2/20 0.32
SLC6A2 P23975 2/20 0.31
DHODH Q02127 1/20 0.31
PDE10A Q9Y233 2/20 0.31
MAPT P10636 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16066214 0.93 MKNK1 (0.37) MKNK1MKNK2MAPK14CDK5CDK5R1
SCHEMBL17033455 0.93 MEN1 (0.37) RAB9ANPY5RPOLBKMT2AKDM4E
SCHEMBL16067222 0.91 MKNK1 (0.35) MKNK1MKNK2MAPK14CDK5CDK5R1
SCHEMBL16066387 0.91 MKNK1 (0.35) MKNK1MKNK2MAPK14CDK5CDK5R1
SCHEMBL16067018 0.89 MKNK1 (0.36) MKNK1MKNK2MAPK14CDK5CDK5R1
SCHEMBL17033524 0.89 CYP2A6 (0.39) MAPT
SCHEMBL17033820 0.87 MKNK1 (0.36) MKNK1MKNK2MAPK14CDK5CDK5R1
SCHEMBL17033490 0.86 KDM4E (0.34) MKNK1MKNK2CYP1A2CYP2C19NPY5R
SCHEMBL17033457 0.86 CCR1 (0.40) MKNK1MKNK2MAPK14CYP1A2NPC1
SCHEMBL17033596 0.85 CYP2A6 (0.38) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015125986-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-08-27 WO disclosed