SCHEMBL17033635

SCHEMBL17033635

COc1ccc(-c2nc(-c3ccc(OC)cc3)nc(-n3c4ccccc4c4ccc5cc6c7ccccc7c7ccccc7n6c5c43)n2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP1B1 Q16678 1/20 0.39
SYK P43405 1/20 0.38
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 3/20 0.36
ABCG2 Q9UNQ0 3/20 0.36
POLB P06746 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPK9 P45984 1/20 0.35
MAPK14 Q16539 1/20 0.35
FLT3 P36888 1/20 0.35
MAPT P10636 2/20 0.35
HPGD P15428 2/20 0.35
HTT P42858 2/20 0.35
HSD17B10 Q99714 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ALOX5 P09917 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17033754 0.88 CYP1A1 (0.39) CYP1A1CYP1A2CYP1B1SYKKDM4E
SCHEMBL17033702 0.88 MEN1 (0.33) KDM4EALDH1A1MEN1KMT2AMAPT
SCHEMBL17033640 0.87 KDM4E (0.33) KDM4EALDH1A1MEN1KMT2AMAPT
SCHEMBL17033834 0.87 CYP1A1 (0.37) CYP1A1CYP1A2CYP1B1SYKKDM4E
SCHEMBL17033641 0.85 PDE10A (0.34) ALDH1A1ABCG2MEN1KMT2AALOX5
SCHEMBL17248154 0.83 CYP1A1 (0.45) CYP1A1CYP1A2CYP1B1SYKKDM4E
SCHEMBL16066197 0.83 CYP1A1 (0.44) CYP1A1CYP1A2CYP1B1SYKKDM4E
SCHEMBL17033534 0.82 CYP1A1 (0.40) CYP1A1CYP1A2CYP1B1SYKKDM4E
SCHEMBL17033653 0.82 MCL1 (0.36) CYP1A2KDM4EALDH1A1KMT2AMAPT
SCHEMBL17033498 0.82 CYP1A1 (0.38) CYP1A1CYP1A2CYP1B1SYKKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015125986-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-08-27 WO disclosed