SCHEMBL17033790

SCHEMBL17033790

c1ccc(-c2cccc(-n3c4ccccc4c4c5cc6c7ccccc7c7ccccc7n6c5ccc43)n2)nc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.39
CCR5 P51681 3/20 0.39
CCR8 P51685 3/20 0.39
KDM4E B2RXH2 3/20 0.39
LMNA P02545 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
HSP90AA1 P07900 2/20 0.39
TP53 P04637 1/20 0.39
ALPL P05186 1/20 0.39
ALPI P09923 1/20 0.39
ALPG P10696 1/20 0.39
ALOX15 P16050 1/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PDE10A Q9Y233 1/20 0.33
METAP1 P53582 4/20 0.33
POLB P06746 2/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17033457 0.87 CCR1 (0.40) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL16066241 0.86 KDM4E (0.37) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL16066434 0.86 KDM4E (0.37) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL17033829 0.86 KDM4E (0.33) KDM4EL3MBTL1POLBMKNK1MKNK2
SCHEMBL17033820 0.86 MKNK1 (0.36) KDM4ELMNAMAPK1HTTPDE10A
SCHEMBL17033819 0.86 MEN1 (0.36) KDM4EL3MBTL1POLB
SCHEMBL16066871 0.85 KDM4E (0.36) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL16066167 0.85 KDM4E (0.40) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL17033644 0.84 KDM4E (0.39) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL16066756 0.84 MCL1 (0.35) CCR1CCR5CCR8KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015125986-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-08-27 WO disclosed