Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL961274 | 0.96 | TDP1 (0.63) | TDP1THRBTSHRLMNAALDH1A1 | |
| SCHEMBL4640656 | 0.94 | TDP1 (0.61) | TDP1THRBTSHRLMNAALDH1A1 | |
| SCHEMBL1398208 | 0.91 | TSHR (0.57) | TDP1THRBTSHRLMNAALDH1A1 | |
| SCHEMBL17034392 | 0.90 | TDP1 (0.73) | TDP1TSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL129437 | 0.86 | TSHR (0.62) | TDP1THRBTSHRLMNAALDH1A1 | |
| SCHEMBL6061655 | 0.86 | TDP1 (0.76) | TDP1TSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL6062602 | 0.86 | TDP1 (0.76) | TDP1TSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL6063097 | 0.86 | TDP1 (0.76) | TDP1TSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL1398204 | 0.86 | TSHR (0.51) | TDP1THRBTSHRLMNAALDH1A1 | |
| SCHEMBL28996621 | 0.85 | TSHR (0.61) | TDP1THRBTSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015126666-A1 | DENTAL COMPOSITION AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-08-27 | — | — | WO | disclosed |