SCHEMBL17034397

SCHEMBL17034397

N#Cc1ccc2c(c1)c1cc(-n3c4ccccc4c4ccccc43)ccc1n2-c1ccc(-c2ccc3c4ccccc4c4ccccc4c3c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PTGER4 P35408 2/20 0.38
PIK3CD O00329 1/20 0.36
PIK3CA P42336 1/20 0.36
PGR P06401 1/20 0.35
HDAC4 P56524 1/20 0.34
USP14 P54578 3/20 0.34
RORC P51449 4/20 0.34
ENPP3 O14638 1/20 0.34
PDPK1 O15530 1/20 0.33
G6PD P11413 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17034468 0.97 KDM4E (0.41) KDM4EATML3MBTL1PTGER4PIK3CD
SCHEMBL15248486 0.96 KDM4E (0.45) KDM4EATML3MBTL1PTGER4PIK3CD
SCHEMBL17032722 0.96 KDM4E (0.45) KDM4EATML3MBTL1PTGER4PIK3CD
SCHEMBL17032779 0.96 KDM4E (0.38) KDM4EATML3MBTL1PTGER4PIK3CD
SCHEMBL18698248 0.96 KDM4E (0.40) KDM4EATML3MBTL1PTGER4PIK3CD
SCHEMBL16941928 0.95 KDM4E (0.41) KDM4EATML3MBTL1PTGER4PIK3CD
SCHEMBL15250616 0.95 KDM4E (0.41) KDM4EATML3MBTL1PTGER4PIK3CD
SCHEMBL17032721 0.94 KDM4E (0.43) KDM4EATML3MBTL1PTGER4PIK3CD
SCHEMBL17034488 0.94 KDM4E (0.38) KDM4EATML3MBTL1PTGER4PIK3CD
SCHEMBL17034464 0.93 KDM4E (0.37) KDM4EATML3MBTL1PTGER4RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230131934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
US-10403825-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-03 US disclosed
US-20150243903-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10403825-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OSBP KDM4E 4278/4885ATM 4635/4885L3MBTL1 930/4885
US-20150243903-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP KDM4E 4278/4885ATM 4635/4885L3MBTL1 930/4885
US-20230131934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP KDM4E 4278/4885ATM 4635/4885L3MBTL1 930/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.