Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.64 |
| ▸ | CA2 | P00918 | 5/20 | 0.59 |
| ▸ | CA1 | P00915 | 4/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | ADH1B | P00325 | 1/20 | 0.46 |
| ▸ | ADH1C | P00326 | 1/20 | 0.46 |
| ▸ | ADH1A | P07327 | 1/20 | 0.46 |
| ▸ | ADH4 | P08319 | 1/20 | 0.46 |
| ▸ | ADH7 | P40394 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1704321 | 1.00 | PPARA (0.64) | PPARACA2CA1EPHX1CA12 | |
| SCHEMBL5020900 | 1.00 | PPARA (0.64) | PPARACA2CA1EPHX1CA12 | |
| SCHEMBL11326328 | 1.00 | PPARA (0.64) | PPARACA2CA1EPHX1CA12 | |
| SCHEMBL10312301 | 1.00 | PPARA (0.64) | PPARACA2CA1EPHX1CA12 | |
| SCHEMBL2694822 | 1.00 | PPARA (0.64) | PPARACA2CA1EPHX1CA12 | |
| SCHEMBL1679669 | 1.00 | PPARA (0.64) | PPARACA2CA1EPHX1CA12 | |
| SCHEMBL11335730 | 1.00 | PPARA (0.64) | PPARACA2CA1EPHX1CA12 | |
| SCHEMBL5696662 | 1.00 | PPARA (0.64) | PPARACA2CA1EPHX1CA12 | |
| Bromide SCHEMBL5709142 | 0.98 | PPARA (0.61) | PPARACA2CA1EPHX1CA12 | |
| SCHEMBL327308 | 0.97 | PPARA (0.60) | PPARACA2CA1EPHX1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632261-B1 | INHIBITORS OF HEPATITIS C VIRUS | PRESIDIO PHARMACEUTICALS INC (US) | 2016-07-13 | — | — | EP | disclosed |
| US-9085587-B2 | Inhibitors of hepatitis C virus | PRESIDIO PHARMACEUTICALS, INC. (US) | 2015-07-21 | — | — | US | disclosed |
| EP-2440527-A1 | PYRIDINYL DERIVATIVES AS INHIBITORS OF ENZYME NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE | Topo Target A/S (DK) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010142735-A1 | PYRIDINYL DERIVATIVES AS INHIBITORS OF ENZYME NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE | TOPOTARGET A/S (DK) | 2010-12-16 | — | — | WO | disclosed |
| EP-1233939-A4 | PROCESS FOR PREPARING OPTICALLY ACTIVE ALPHA-HYDROXY ACIDS AND DERIVATIVES THEREOF | SCINOPHARM SINGAPORE PTE LTD (SG) | 2003-07-09 | — | — | EP | disclosed |
| EP-1233939-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE ALPHA-HYDROXY ACIDS AND DERIVATIVES THEREOF | Scinopharm Singapore Pte Ltd. (SG) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001040153-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE α-HYDROXY ACIDS AND DERIVATIVES THEREOF | SCINOPHARM SINGAPORE PTE LTD. (SG) | 2001-06-07 | — | — | WO | disclosed |
| US-4812463-A | CARBONIC ANHYDRASE INHIBITORS | MERCK & CO., INC. (US) | 1989-03-14 | — | — | US | disclosed |
| EP-0252640-A1 | Alkanesulfonamides as antiglaucoma agents | MERCK & CO. INC. (US) | 1988-01-13 | — | — | EP | disclosed |