⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10153710 | 0.78 | — | — | |
| SCHEMBL6778465 | 0.75 | — | — | |
| SCHEMBL15993879 | 0.75 | — | — | |
| SCHEMBL15994076 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL27634675 | 0.75 | — | — | |
| SCHEMBL24050459 | 0.73 | — | — | |
| SCHEMBL8709678 | 0.71 | — | — | |
| SCHEMBL4954303 | 0.71 | — | — | |
| SCHEMBL15993794 | 0.71 | — | — | |
| SCHEMBL10050949 | 0.71 | MAPT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117730083-A | Pyrimidine compounds as MAP4K1 inhibitors | 格兰马克专业公司 | 2024-03-19 | — | — | CN | claimed |
| CN-117500507-A | Phosphorus derivatives as novel SOS1 inhibitors | 拜耳公司 | 2024-02-02 | — | — | CN | claimed |
| CN-117015548-A | Synthetic ursolic acid derivatives and methods of use thereof | 里亚塔医药公司 | 2023-11-07 | — | — | CN | claimed |
| CN-107108647-A | Substituted pyridine compounds having herbicidal activity | 巴斯夫欧洲公司 | 2017-08-29 | — | — | CN | claimed |
| US-20100298392-A1 | Isoindoline Derivatives For The Treatment Of Arrhythmias | ASTRAZENECA AB (SE) | 2010-11-25 | — | — | US | claimed |
| EP-2049484-A1 | ISOINDOLINE DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIAS | AstraZeneca AB (SE) | 2009-04-22 | — | — | EP | claimed |
| WO-2008008022-A1 | ISOINDOLINE DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2008-01-17 | — | — | WO | claimed |
| US-20080015237-A1 | NEW COMPOUNDS I/418 | ASTRAZENECA AB (SE) | 2008-01-17 | — | — | US | claimed |
| EP-4676480-A1 | INHIBITORS OF DNA POLYMERASE THETA | Breakpoint Therapeutics GmbH (DE) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024189493-A1 | INHIBITORS OF DNA POLYMERASE THETA | BREAKPOINT THERAPEUTICS GMBH (DE) | 2024-09-19 | — | — | WO | disclosed |
| US-20240293401-A1 | COMBINATION THERAPY WITH AN LXR AGONIST AND AN INHIBITOR COMPOUND | Asteroid Therapeutics (US) | 2024-09-05 | — | — | US | disclosed |
| CN-117730083-A | Pyrimidine compounds as MAP4K1 inhibitors | 格兰马克专业公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-117715642-A | Heterocyclic compounds and methods of use | 薛定谔公司 | 2024-03-15 | — | — | CN | disclosed |
| EP-3827241-B1 | DISSOCIATION OF BIOLOGICAL SAMPLES | GOLDSBOROUGH ANDREW SIMON (FR) | 2024-03-13 | — | — | EP | disclosed |
| EP-2208729-A1 | OXAZOLIDINONE DERIVATIVE HAVING 7-MEMBERED HETERO RING | Research Foundation Itsuu Laboratory (JP) | 2010-07-21 | — | — | EP | disclosed |
| EP-2049484-A1 | ISOINDOLINE DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIAS | AstraZeneca AB (SE) | 2009-04-22 | — | — | EP | disclosed |
| WO-2009018116-A1 | PROCESS FOR FLUORINATION USING 1,1,2,2-TETRAFLUOROETHYL-N,N-DIMETHYLAMINE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-02-05 | — | — | WO | disclosed |
| US-7485693-B2 | Primer composition for a fluorinated elastomer or a fluorinated gel | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2009-02-03 | — | — | US | disclosed |
| WO-2008008022-A1 | ISOINDOLINE DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2008-01-17 | — | — | WO | disclosed |
| US-20080015237-A1 | NEW COMPOUNDS I/418 | ASTRAZENECA AB (SE) | 2008-01-17 | — | — | US | disclosed |