Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1703696 | 1.00 | TLR7 (0.75) | TLR7 | |
| SCHEMBL1008795 | 0.91 | TLR7 (0.78) | TLR7 | |
| SCHEMBL1008793 | 0.91 | TLR7 (0.78) | TLR7 | |
| SCHEMBL12287585 | 0.90 | TLR7 (0.62) | TLR7 | |
| SCHEMBL15355107 | 0.88 | TLR7 (0.80) | TLR7 | |
| SCHEMBL12841255 | 0.87 | TLR7 (0.71) | TLR7 | |
| SCHEMBL16997005 | 0.86 | TLR7 (0.78) | TLR7 | |
| SCHEMBL1009182 | 0.86 | TLR7 (0.77) | TLR7 | |
| SCHEMBL1527520 | 0.85 | TLR7 (1.00) | TLR7 | |
| SCHEMBL1527517 | 0.85 | TLR7 (1.00) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558069-A1 | BENZONAPTHYRIDINE COMPOSITIONS AND USES THEREOF | Novartis AG (CH) | 2013-02-20 | — | — | EP | disclosed |
| EP-2440245-A1 | BENZONAPHTHYRIDINE-CONTAINING VACCINES | Novartis AG (CH) | 2012-04-18 | — | — | EP | disclosed |
| WO-2011130379-A1 | BENZONAPTHYRIDINE COMPOSITIONS AND USES THEREOF | NOVARTIS AG (CH) | 2011-10-20 | — | — | WO | disclosed |
| WO-2010144734-A1 | BENZONAPHTHYRIDINE-CONTAINING VACCINES | NOVARTIS AG (CH) | 2010-12-16 | — | — | WO | disclosed |