Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 13/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 11/20 | 0.51 |
| ▸ | SIRT5 | Q9NXA8 | 6/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17039829 | 0.97 | SIRT2 (0.49) | SIRT2SIRT1SIRT5SIRT3 | |
| SCHEMBL17039823 | 0.97 | SIRT2 (0.49) | SIRT2SIRT1SIRT5SIRT3 | |
| SCHEMBL17039854 | 0.97 | SIRT2 (0.51) | SIRT2SIRT1SIRT5SIRT3 | |
| SCHEMBL17040113 | 0.97 | SIRT2 (0.51) | SIRT2SIRT1SIRT5SIRT3 | |
| SCHEMBL17039824 | 0.90 | CA12 (0.52) | SIRT2SIRT1SIRT5SIRT3 | |
| SCHEMBL31681810 | 0.88 | SIRT2 (0.60) | SIRT2SIRT1SIRT5SIRT3 | |
| SCHEMBL30449814 | 0.88 | SIRT2 (0.60) | SIRT2SIRT1SIRT5SIRT3 | |
| SCHEMBL17039825 | 0.87 | CA12 (0.49) | SIRT2SIRT1SIRT5SIRT3 | |
| SCHEMBL17039858 | 0.87 | CA12 (0.51) | SIRT2SIRT1SIRT5SIRT3 | |
| SCHEMBL17039856 | 0.87 | CA12 (0.51) | SIRT2SIRT1SIRT5SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015123783-A1 | CATHEPSIN B-TARGETING PROBES | THUNDER BAY REGIONAL RESEARCH INSTITUTE (CA) | 2015-08-27 | — | — | WO | disclosed |