Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 19/20 | 0.71 |
| ▸ | FLT4 | P35916 | 9/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15588322 | 0.85 | FLT4 (0.73) | PTK2FLT4 | |
| SCHEMBL15524679 | 0.85 | FLT4 (0.73) | PTK2FLT4 | |
| SCHEMBL12478568 | 0.83 | PTK2 (1.00) | PTK2FLT4 | |
| SCHEMBL12479250 | 0.82 | PTK2 (1.00) | PTK2FLT4 | |
| Narmafotinib SCHEMBL12479576 | 0.82 | PTK2 (1.00) | PTK2FLT4 | |
| Narmafotinib SCHEMBL30354504 | 0.82 | PTK2 (1.00) | PTK2FLT4 | |
| SCHEMBL12479561 | 0.81 | PTK2 (0.84) | PTK2FLT4 | |
| SCHEMBL12479598 | 0.81 | PTK2 (0.87) | PTK2FLT4 | |
| SCHEMBL14635961 | 0.81 | PTK2 (1.00) | PTK2FLT4 | |
| SCHEMBL14635753 | 0.79 | PTK2 (0.80) | PTK2FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015123722-A1 | INHIBITORS | BIONOMICS LIMITED (AU) | 2015-08-27 | — | — | WO | disclosed |