SCHEMBL17040243

SCHEMBL17040243

NCC(N)(CF)CF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8332731 0.79
Hydrochloric Acid SCHEMBL5256487 0.75
SCHEMBL3797709 0.74
SCHEMBL10002462 0.67
SCHEMBL19268292 0.67
SCHEMBL27855169 0.65
SCHEMBL3901824 0.64
Hydrochloric Acid SCHEMBL27871837 0.62
Hydrochloric Acid SCHEMBL27871834 0.62
SCHEMBL15382405 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3107920-B1 3-(PYRIMIDINE-2-YL)IMIDAZO[1,2-A]PYRIDINES Bayer Pharma AG (DE) 2017-10-18 EP disclosed
EP-3107920-B1 3-(PYRIMIDINE-2-YL)IMIDAZO[1,2-A]PYRIDINES Bayer Pharma AG (DE) 2017-10-18 EP disclosed
US-20170240566-A1 AMINO-SUBSTITUTED ANNULATED PYRIMIDINES AND USE THEREOF BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2017-08-24 US disclosed
US-20170240566-A1 AMINO-SUBSTITUTED ANNULATED PYRIMIDINES AND USE THEREOF BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2017-08-24 US disclosed
US-20170240566-A1 AMINO-SUBSTITUTED ANNULATED PYRIMIDINES AND USE THEREOF BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2017-08-24 US disclosed
CN-107074883-A Cyclic pyrimidin of amino substitution and application thereof 拜耳医药股份有限公司 2017-08-18 CN disclosed
EP-3186255-A1 AMINO-SUBSTITUTED ANNULATED PYRIMIDINES AND USE THEREOF Bayer Pharma Aktiengesellschaft (DE) 2017-07-05 EP disclosed
US-9688699-B2 3-(pyrimidine-2-yl)imidazo[1,2-a]pyridines BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2017-06-27 US disclosed
US-9688699-B2 3-(pyrimidine-2-yl)imidazo[1,2-a]pyridines BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2017-06-27 US disclosed
US-9688699-B2 3-(pyrimidine-2-yl)imidazo[1,2-a]pyridines BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2017-06-27 US disclosed
CN-106459090-A 3-(pyrimidine-2-yl)imidazo[1,2-A]pyridines 拜耳制药股份公司 2017-02-22 CN disclosed
US-20160347770-A1 3-(PYRIMIDINE-2-YL)IMIDAZO[1,2-A]PYRIDINES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2016-12-01 US disclosed
US-20160347770-A1 3-(PYRIMIDINE-2-YL)IMIDAZO[1,2-A]PYRIDINES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2016-12-01 US disclosed
US-20160347770-A1 3-(PYRIMIDINE-2-YL)IMIDAZO[1,2-A]PYRIDINES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2016-12-01 US disclosed
WO-2016030354-A1 AMINO-SUBSTITUTED ANNULATED PYRIMIDINES AND USE THEREOF BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2016-03-03 WO disclosed
WO-2016030354-A1 AMINO-SUBSTITUTED ANNULATED PYRIMIDINES AND USE THEREOF BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2016-03-03 WO disclosed
WO-2015124544-A1 3-(PYRIMIDINE-2-YL)IMIDAZO[1,2-A]PYRIDINES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2015-08-27 WO disclosed