⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13902383 | 1.00 | — | — | |
| SCHEMBL7736856 | 1.00 | — | — | |
| SCHEMBL2055568 | 1.00 | — | — | |
| SCHEMBL2055570 | 1.00 | — | — | |
| SCHEMBL3089367 | 0.78 | — | — | |
| SCHEMBL625447 | 0.78 | — | — | |
| SCHEMBL3089364 | 0.78 | — | — | |
| SCHEMBL14490647 | 0.78 | — | — | |
| SCHEMBL19448335 | 0.78 | — | — | |
| SCHEMBL2801704 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9586931-B2 | Triazolyl derivatives as Syk inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-03-07 | — | — | US | disclosed |
| US-20150239866-A1 | TRIAZOLYL DERIVATIVES AS SYK INHIBITORS | MERCK CANADA INC. (CA) | 2015-08-27 | — | — | US | disclosed |