SCHEMBL1704074

SCHEMBL1704074

O=C(O)C(O)c1ccco1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 1.00
POLB P06746 2/20 1.00
PTPN1 P18031 2/20 1.00
L3MBTL1 Q9Y468 2/20 1.00
PKM P14618 1/20 1.00
PTPN7 P35236 1/20 1.00
BLM P54132 1/20 1.00
ESR2 Q92731 1/20 1.00
MEN1 O00255 2/20 0.62
AGTR1 P30556 1/20 0.62
ALDH1A1 P00352 3/20 0.58
MAPT P10636 2/20 0.58
KDM4E B2RXH2 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
HSD17B10 Q99714 1/20 0.48
LMNA P02545 2/20 0.48
MAPK1 P28482 1/20 0.48
CYP2C19 P33261 2/20 0.46
MIF P14174 1/20 0.44
CES2 O00748 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10430342 1.00 KMT2A (1.00) KMT2APOLBPTPN1L3MBTL1PKM
SCHEMBL10430343 1.00 KMT2A (1.00) KMT2APOLBPTPN1L3MBTL1PKM
SCHEMBL525255 0.84 KMT2A (0.72) KMT2APOLBPTPN1L3MBTL1PKM
SCHEMBL15388844 0.82 KMT2A (0.69) KMT2APOLBPTPN1L3MBTL1PKM
SCHEMBL27495771 0.80 KMT2A (0.67) KMT2APOLBPTPN1L3MBTL1PKM
SCHEMBL27391080 0.80 KMT2A (0.67) KMT2APOLBPTPN1L3MBTL1PKM
SCHEMBL5319337 0.80 KMT2A (0.67) KMT2APOLBPTPN1L3MBTL1PKM
SCHEMBL29241351 0.79 KMT2A (0.66) KMT2APOLBPTPN1L3MBTL1PKM
SCHEMBL9318301 0.79 KMT2A (0.65) KMT2APOLBPTPN1L3MBTL1PKM
SCHEMBL4753938 0.79 KMT2A (0.65) KMT2APOLBPTPN1L3MBTL1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119118967-A Preparation method of 2-furanone acid 重庆新征程生物医药有限公司 2024-12-13 CN claimed
WO-2009083551-A1 PROCESS FOR PREPARING CARBOXYLIC ESTERS BIOREFINERY.DE GMBH (DE) 2009-07-09 WO claimed
US-20090105240-A1 Methods for treating leukemia and myelodysplastic syndrome, and methods for identifying agents for treating same SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE 2009-04-23 US claimed
US-6740731-B2 COMPRISING A HYDROXYCARBOXYLIC ACID-CONTAINING POLYMER WHERE THE POLYMER BIODEGRADES HYDROLYTICALLY DURING STORAGE, USE AND DISPOSAL STAGES IN A CONTROLLED MANNER,THE RATE BEING ACCELERATED DURING DISPOSAL; MICROBIOCIDES CARGILL DOW POLYMERS LLC 2004-05-25 US claimed
US-20020123546-A1 Degradation control of environmentally degradable disposable materials ECOPOL, LLC 2002-09-05 US claimed
EP-0722433-B1 METHOD TO PRODUCE CYCLIC ESTERS BIOPAK TECHNOLOGY LTD (US) 2000-01-26 EP claimed
JP-2922303-B2 1999-07-19 JP claimed
EP-0632807-B1 PROCESS FOR THE PRODUCTION OF CYCLIC ESTERS FROM HYDROXY ACIDS AND DERIVATIVES THEREOF BIOPAK TECHNOLOGY LTD (US) 1998-08-19 EP claimed
CN-1186491-A Method to produce and purity cyclic esters CHRONOPOL INC (US) 1998-07-01 CN claimed
EP-0830358-A1 METHOD TO PRODUCE AND PURIFY CYCLIC ESTERS Chronopol, Inc. (US) 1998-03-25 EP claimed
EP-0662107-A4 DEGRADATION CONTROL OF ENVIRONMENTALLY DEGRADABLE DISPOSABLE MATERIALS. BIOPAK TECHNOLOGY LTD (US) 1995-09-27 EP claimed
EP-0662107-A1 DEGRADATION CONTROL OF ENVIRONMENTALLY DEGRADABLE DISPOSABLE MATERIALS BioPak Technology, Ltd. (US) 1995-07-12 EP claimed
US-5420304-A Esterification and cyclization then solvent extraction BIOPAK TECHNOLOGY, LTD. (US) 1995-05-30 US claimed
EP-0632807-A4 PROCESS FOR THE PRODUCTION OF CYCLIC ESTERS FROM HYDROXY ACIDS AND DERIVATIVES THEREOF. BIOPAK TECHNOLOGY LTD (US) 1995-05-03 EP claimed
WO-1995009142-A1 METHOD TO PRODUCE CYCLIC ESTERS BIOPAK TECHNOLOGY, LTD. (US) 1995-04-06 WO claimed
EP-0632807-A1 PROCESS FOR THE PRODUCTION OF CYCLIC ESTERS FROM HYDROXY ACIDS AND DERIVATIVES THEREOF BIOPAK TECHNOLOGY LTD (US) 1995-01-11 EP claimed
US-5319107-A By direct dehydration of hydroxy carboxylic acids or derivatives; lactide, glycolide BIOPAK TECHNOLOGY, LTD. (US) 1994-06-07 US claimed
WO-1994006866-A1 DEGRADATION CONTROL OF ENVIRONMENTALLY DEGRADABLE DISPOSABLE MATERIALS BIOPAK TECHNOLOGY, LTD. (US) 1994-03-31 WO claimed
CN-1080921-A The method for preparing cyclic ester with hydroxy acid and derivative thereof BIOPAK TECHNOLOGY LTD (US) 1994-01-19 CN claimed
WO-1993019058-A2 PROCESS FOR THE PRODUCTION OF CYCLIC ESTERS FROM HYDROXY ACIDS AND DERIVATIVES THEREOF BIOPAK TECHNOLOGY LTD. (US) 1993-09-30 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105240-A1 Methods for treating leukemia and myelodysplastic syndrome, and methods for identifying agents for treating same MCL1, AS3MT, MYADM KMT2A 848/4885POLB 819/4885PTPN1 2481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.