⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26346693 | 1.00 | — | — | |
| SCHEMBL23422898 | 1.00 | — | — | |
| SCHEMBL17040773 | 0.77 | — | — | |
| SCHEMBL2529701 | 0.75 | — | — | |
| SCHEMBL6689162 | 0.73 | — | — | |
| SCHEMBL2382845 | 0.73 | — | — | |
| SCHEMBL14606090 | 0.70 | — | — | |
| SCHEMBL25362808 | 0.70 | — | — | |
| SCHEMBL29542533 | 0.70 | — | — | |
| SCHEMBL16856366 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183331-A1 | MODIFIED TNF-ALPHA ANTIBODIES AND USES THEREOF | BRIGHT PEAK THERAPEUTICS AG (CH) | 2023-06-15 | — | — | US | disclosed |
| WO-2015124443-A1 | METHOD FOR THE GENERATION OF CHEMICAL LIBRARIES | ETH ZURICH (CH) | 2015-08-27 | — | — | WO | disclosed |