Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3041368 | 0.82 | PTGDR2 (0.47) | HPGDTSHRPTGDR2CYP2C9MAPT | |
| SCHEMBL3709150 | 0.81 | PTGDR2 (0.67) | PTGDR2CYP2C9 | |
| SCHEMBL19460038 | 0.80 | PTGDR2 (0.40) | PTGDR2CYP2C9 | |
| SCHEMBL16957385 | 0.77 | TSHR (0.47) | HPGDTSHRPTGDR2HTR2CHTR2B | |
| SCHEMBL17040984 | 0.77 | TSHR (0.47) | HPGDTSHRPTGDR2HTR2CHTR2B | |
| SCHEMBL1197763 | 0.77 | MAPT (0.54) | HPGDTSHRHTR2CHTR2BHTR2A | |
| SCHEMBL12145814 | 0.76 | PTGDR2 (0.48) | PTGDR2CYP2C9 | |
| Hydrochloric Acid SCHEMBL27743366 | 0.76 | MAPT (0.52) | HPGDTSHRHTR2CHTR2BHTR2A | |
| SCHEMBL29172852 | 0.74 | TP53 (0.39) | TSHRPTGDR2HTR2B | |
| SCHEMBL16692012 | 0.74 | FGFR2 (0.36) | HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015125785-A1 | PYRAZOLONE DERIVATIVE HAVING MULTIPLE SUBSTITUENTS | 第一三共株式会社 | 2015-08-27 | — | — | WO | disclosed |