Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | PREP | P48147 | 4/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22086379 | 1.00 | CHRM2 (0.50) | CHRM2CHRM1CHRM3PREPPTPN1 | |
| SCHEMBL6126947 | 1.00 | CHRM2 (0.50) | CHRM2CHRM1CHRM3PREPPTPN1 | |
| SCHEMBL6126949 | 1.00 | CHRM2 (0.50) | CHRM2CHRM1CHRM3PREPPTPN1 | |
| SCHEMBL17040993 | 0.93 | CHRM2 (0.45) | CHRM2CHRM1CHRM3PREPPTPN1 | |
| SCHEMBL21897453 | 0.93 | CHRM2 (0.45) | CHRM2CHRM1CHRM3PREPPTPN1 | |
| SCHEMBL6121165 | 0.93 | CHRM2 (0.45) | CHRM2CHRM1CHRM3PREPPTPN1 | |
| SCHEMBL6121160 | 0.93 | CHRM2 (0.45) | CHRM2CHRM1CHRM3PREPPTPN1 | |
| SCHEMBL5832187 | 0.90 | CHRM2 (0.49) | CHRM2CHRM1CHRM3PREPPTPN1 | |
| SCHEMBL17014473 | 0.90 | CHRM2 (0.49) | CHRM2CHRM1CHRM3PREPPTPN1 | |
| SCHEMBL15773749 | 0.90 | CHRM2 (0.49) | CHRM2CHRM1CHRM3PREPPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015125785-A1 | PYRAZOLONE DERIVATIVE HAVING MULTIPLE SUBSTITUENTS | 第一三共株式会社 | 2015-08-27 | — | — | WO | disclosed |