Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92905 | 0.75 | IDO1 (0.58) | RECQLSMN1; SMN2IDO1S1PR1PNMT | |
| SCHEMBL13300191 | 0.73 | TSHR (0.48) | SMN1; SMN2HPGDIDO1TP53HSD17B10 | |
| SCHEMBL21886001 | 0.72 | EGFR (0.37) | RECQLTTRMAPTHSD17B10ENPP2 | |
| SCHEMBL2982854 | 0.71 | TTR (0.53) | RECQLTTRHPGDMAPTHSD17B10 | |
| SCHEMBL31621229 | 0.71 | RECQL (0.43) | RECQLTTRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19114149 | 0.71 | POLB (0.43) | TTRNPC1RAB9AHTTALOX15 | |
| SCHEMBL93063 | 0.70 | S1PR1 (0.51) | RECQLTTRSMN1; SMN2S1PR1HSD17B10 | |
| SCHEMBL5430585 | 0.70 | RECQL (0.42) | RECQLTTRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2092848 | 0.70 | MAPT (0.45) | RECQLTTRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL263603 | 0.70 | NOTUM (0.44) | RECQLTTRNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3456713-A1 | PROCESS FOR THE PREPARATION OF TRIAZINE DERIVATIVES | Japan Tobacco Inc. (JP) | 2019-03-20 | — | — | EP | disclosed |
| WO-2015125842-A1 | TRIAZINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | 日本たばこ産業株式会社 | 2015-08-27 | — | — | WO | disclosed |