Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 11/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 6/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4057114 | 0.96 | TLR7 (0.42) | TLR7CSNK2A2CSNK2BCSNK2A1MAP4K4 | |
| SCHEMBL1062650 | 0.91 | CSNK2A1 (0.44) | TLR7CSNK2A1 | |
| SCHEMBL1060846 | 0.90 | TLR7 (0.43) | TLR7 | |
| SCHEMBL1061504 | 0.85 | ADORA2A (0.41) | TLR7 | |
| SCHEMBL1060956 | 0.85 | TLR7 (0.42) | TLR7 | |
| SCHEMBL1704121 | 0.84 | MAP4K4 (0.37) | TLR7CSNK2A2CSNK2BCSNK2A1MAP4K4 | |
| SCHEMBL1008663 | 0.81 | TLR7 (0.39) | TLR7 | |
| SCHEMBL1008266 | 0.81 | TLR7 (0.47) | TLR7 | |
| SCHEMBL1675554 | 0.79 | TLR7 (0.43) | TLR7 | |
| SCHEMBL1008090 | 0.78 | TLR7 (0.43) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440245-A1 | BENZONAPHTHYRIDINE-CONTAINING VACCINES | Novartis AG (CH) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010144734-A1 | BENZONAPHTHYRIDINE-CONTAINING VACCINES | NOVARTIS AG (CH) | 2010-12-16 | — | — | WO | disclosed |