Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 10/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17043298 | 1.00 | PTPN1 (0.51) | PTPN1HPGDPOLBMAOAMAOB | |
| SCHEMBL17043297 | 1.00 | PTPN1 (0.51) | PTPN1HPGDPOLBMAOAMAOB | |
| SCHEMBL17043988 | 0.93 | PTPN1 (0.51) | PTPN1HPGDPOLBMAOAMAOB | |
| SCHEMBL1915173 | 0.93 | PTPN1 (0.51) | PTPN1HPGDPOLBMAOAMAOB | |
| SCHEMBL17043986 | 0.93 | PTPN1 (0.51) | PTPN1HPGDPOLBMAOAMAOB | |
| SCHEMBL17043819 | 0.89 | PTPN1 (0.46) | PTPN1HPGDPOLBMAOAMAOB | |
| SCHEMBL17043404 | 0.89 | PTPN1 (0.46) | PTPN1HPGDPOLBMAOAMAOB | |
| SCHEMBL17043400 | 0.89 | PTPN1 (0.46) | PTPN1HPGDPOLBMAOAMAOB | |
| SCHEMBL17043820 | 0.89 | PTPN1 (0.46) | PTPN1HPGDPOLBMAOAMAOB | |
| SCHEMBL17043403 | 0.89 | PTPN1 (0.46) | PTPN1HPGDPOLBMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516425-B1 | AMINOPYRIMIDINE KINASE INHIBITORS | JASCO PHARMACEUTICALS LLC (US) | 2015-09-02 | — | — | EP | disclosed |