Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.54 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17043609 | 1.00 | HPGD (0.54) | HPGDPIM1HTR2AHTR2CMTOR | |
| SCHEMBL17043611 | 1.00 | HPGD (0.54) | HPGDPIM1HTR2AHTR2CMTOR | |
| SCHEMBL17043384 | 0.91 | HPGD (0.52) | HPGDPIM1HTR2AHTR2CMTOR | |
| SCHEMBL17043390 | 0.91 | HPGD (0.52) | HPGDPIM1HTR2AHTR2CMTOR | |
| SCHEMBL17043387 | 0.91 | HPGD (0.52) | HPGDPIM1HTR2AHTR2CMTOR | |
| SCHEMBL17043286 | 0.89 | HPGD (0.49) | HPGDPIM1HTR2AHTR2CMTOR | |
| SCHEMBL17043285 | 0.89 | HPGD (0.49) | HPGDPIM1HTR2AHTR2CMTOR | |
| SCHEMBL17043283 | 0.89 | HPGD (0.49) | HPGDPIM1HTR2AHTR2CMTOR | |
| SCHEMBL17043775 | 0.89 | HPGD (0.49) | HPGDPIM1HTR2AHTR2CMTOR | |
| SCHEMBL17043772 | 0.89 | HPGD (0.49) | HPGDPIM1HTR2AHTR2CMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516425-B1 | AMINOPYRIMIDINE KINASE INHIBITORS | JASCO PHARMACEUTICALS LLC (US) | 2015-09-02 | — | — | EP | disclosed |