SCHEMBL1704392

SCHEMBL1704392

Cc1ccc(CCc2cnc3c(N)nc4cc(C(=O)O)ccc4c3c2)c(C)c1

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1062056 0.96 TLR7 (0.68) TLR7
SCHEMBL1060679 0.90 TLR7 (0.66) TLR7
SCHEMBL1008680 0.89 TLR7 (0.73) TLR7
SCHEMBL1062942 0.88 TLR7 (0.68) TLR7
SCHEMBL1062572 0.87 TLR7 (0.67) TLR7
SCHEMBL1057766 0.87 TLR7 (0.58) TLR7
SCHEMBL1008073 0.86 TLR7 (0.68) TLR7
SCHEMBL1009032 0.86 TLR7 (0.68) TLR7
SCHEMBL1008627 0.86 TLR7 (0.65) TLR7
SCHEMBL1081992 0.85 TLR7 (0.67) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2440245-A1 BENZONAPHTHYRIDINE-CONTAINING VACCINES Novartis AG (CH) 2012-04-18 EP disclosed
WO-2010144734-A1 BENZONAPHTHYRIDINE-CONTAINING VACCINES NOVARTIS AG (CH) 2010-12-16 WO disclosed