⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7500495 | 0.85 | — | — | |
| SCHEMBL16484245 | 0.85 | — | — | |
| SCHEMBL5436685 | 0.82 | PTPN1 (0.46) | — | |
| SCHEMBL5436688 | 0.82 | PTPN1 (0.46) | — | |
| SCHEMBL14054336 | 0.80 | CA1 (0.36) | — | |
| SCHEMBL23829915 | 0.78 | — | — | |
| SCHEMBL5499702 | 0.78 | — | — | |
| SCHEMBL5184171 | 0.78 | — | — | |
| SCHEMBL3247704 | 0.78 | — | — | |
| SCHEMBL309566 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2888268-B1 | NOVEL SPIROOXINDOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | OKINAWA INST SCIENCE & TECH SCHOOL CORP (JP) | 2018-08-22 | — | — | EP | disclosed |
| US-9309261-B2 | Spirooxindole derivative and process for producing the same | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2016-04-12 | — | — | US | disclosed |
| US-20150246927-A1 | NOVEL SPIROOXINDOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2015-09-03 | — | — | US | disclosed |