SCHEMBL1704710

SCHEMBL1704710

Oc1ccc2c(Cl)cc(Cl)cc2n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.44
TSHR P16473 3/20 0.39
HSD17B10 Q99714 3/20 0.39
ALDH1A1 P00352 2/20 0.39
CYP3A4 P08684 1/20 0.39
RECQL P46063 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 2/20 0.37
NR4A2 P43354 1/20 0.37
PDE10A Q9Y233 1/20 0.36
ESR1 P03372 2/20 0.36
ESR2 Q92731 2/20 0.36
PIK3R1 P27986 1/20 0.36
PIK3CA P42336 1/20 0.36
HPGD P15428 1/20 0.35
ESRRB O95718 1/20 0.35
ESRRA P11474 1/20 0.35
MPO P05164 1/20 0.35
KMT2A Q03164 1/20 0.35
BCHE P06276 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1612195 0.81 NT5E (0.37) MAPTESR1ESR2ESRRBESRRA
SCHEMBL3972257 0.79 HRH3 (0.46) HRH3ALDH1A1POLBMAPTNR4A2
SCHEMBL5258862 0.76 POLB (0.56) HRH3POLBMAPTNR4A2PDE10A
SCHEMBL5258857 0.76 HRH3 (0.44) HRH3ALDH1A1POLBMAPTNR4A2
SCHEMBL7813478 0.76 S1PR4 (0.45) HRH3POLBNR4A2PDE10AESR1
SCHEMBL9394762 0.74 MGAM (0.44) HRH3TSHRMAPT
SCHEMBL7045373 0.73 CYP1A2 (0.42) TSHRALDH1A1MAPTKMT2ABCHE
SCHEMBL28829501 0.73 HRH3 (0.42) HRH3ALDH1A1CYP3A4POLBMAPT
SCHEMBL14720338 0.72 NR4A2 (0.50) HRH3TSHRHSD17B10ALDH1A1CYP3A4
SCHEMBL8127677 0.72 POLB (0.47) TSHRHSD17B10ALDH1A1CYP3A4POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11607392-B2 Encapsulation system for prolonged release of active agents TREND INNOVATIONS (CA) 2023-03-21 US disclosed
US-20200297648-A1 ENCAPSULATION SYSTEM FOR PROLONGED RELEASE OF ACTIVE AGENTS TREND INNOVATIONS (CA) 2020-09-24 US disclosed
WO-2019053689-A1 ENCAPSULATION SYSTEM FOR PROLONGED RELEASE OF ACTIVE AGENTS TREND INNOVATIONS (CA) 2019-03-21 WO disclosed
EP-2440044-A2 INORGANIC CARRIER MATERIALS CONTAINING NITROGEN Lanxess Deutschland GmbH (DE) 2012-04-18 EP disclosed
WO-2010142795-A2 INORGANIC CARRIER MATERIALS CONTAINING NITROGEN LANXESS DEUTSCHLAND GMBH (DE) 2010-12-16 WO disclosed