⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2432547 | 0.74 | — | — | |
| SCHEMBL8966968 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL28193326 | 0.70 | — | — | |
| Bromide SCHEMBL3536421 | 0.70 | — | — | |
| SCHEMBL31123140 | 0.63 | — | — | |
| SCHEMBL11285820 | 0.63 | — | — | |
| SCHEMBL28218 | 0.63 | — | — | |
| SCHEMBL5944 | 0.63 | — | — | |
| SCHEMBL788702 | 0.63 | — | — | |
| SCHEMBL14112035 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10925881-B2 | Treatment of conditions associated with hyperinsulinaemia | TENSHA THERAPEUTICS, INC. (US) | 2021-02-23 | — | — | US | disclosed |
| US-20170209461-A1 | Treatment Of Conditions Associated With Hyperinsulinaemia | TENSHA THERAPEUTICS, INC. | 2017-07-27 | — | — | US | disclosed |
| CN-106456653-A | Treatment of conditions associated with hyperinsulinaemia | 腾沙治疗公司 | 2017-02-22 | — | — | CN | disclosed |
| EP-3110424-A1 | TREATMENT OF CONDITIONS ASSOCIATED WITH HYPERINSULINAEMIA | Tensha Therapeutics, Inc. (US) | 2017-01-04 | — | — | EP | disclosed |
| WO-2015131113-A1 | TREATMENT OF CONDITIONS ASSOCIATED WITH HYPERINSULINAEMIA | TENSHA THERAPEUTICS, INC. (US) | 2015-09-03 | — | — | WO | disclosed |