SCHEMBL17047779

SCHEMBL17047779

CCC(Cc1ccc(-c2ccc(O)cc2)cc1)c1ccc(O)cc1

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 15/20 0.89
ESR2 Q92731 14/20 0.89
SLC6A2 P23975 2/20 0.48
CYP1A2 P05177 2/20 0.48
CYP3A4 P08684 2/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
LMNA P02545 1/20 0.48
PGR P06401 1/20 0.48
CHRM2 P08172 1/20 0.48
ADORA3 P0DMS8 1/20 0.48
AR P10275 1/20 0.48
CYP2D6 P10635 1/20 0.48
MAPT P10636 1/20 0.48
CHRM1 P11229 1/20 0.48
ALOX15 P16050 1/20 0.48
DRD1 P21728 1/20 0.48
TBXA2R P21731 1/20 0.48
PTGS1 P23219 1/20 0.48
ADRA1A P35348 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isobutesrol SCHEMBL5694505 0.94 ESR1 (1.00) ESR1ESR2SLC6A2CYP1A2CYP3A4
SCHEMBL1833902 0.89 ESR1 (0.89) ESR1ESR2SLC6A2CYP1A2CYP3A4
SCHEMBL1838502 0.87 ESR1 (0.86) ESR1ESR2SLC6A2CYP1A2CYP3A4
SCHEMBL28059678 0.86 ESR1 (0.83) ESR1ESR2SLC6A2CYP1A2CYP3A4
SCHEMBL1838575 0.86 ESR1 (0.83) ESR1ESR2SLC6A2CYP1A2CYP3A4
SCHEMBL1836841 0.85 ESR1 (0.82) ESR1ESR2SLC6A2CYP1A2CYP3A4
SCHEMBL27833227 0.85 ESR1 (0.82) ESR1ESR2SLC6A2CYP1A2CYP3A4
SCHEMBL1839664 0.83 ESR1 (0.77) ESR1ESR2SLC6A2CYP1A2CYP3A4
SCHEMBL6744903 0.82 ESR1 (0.76) ESR1ESR2SLC6A2CYP1A2CYP3A4
SCHEMBL1836043 0.82 ESR1 (0.75) ESR1ESR2SLC6A2CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015130274-A1 TUNABLE THERMOSTATIC MATERIALS AND METHODS FOR PREPARATION AND USE EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2015-09-03 WO claimed
WO-2015130274-A1 TUNABLE THERMOSTATIC MATERIALS AND METHODS FOR PREPARATION AND USE EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2015-09-03 WO disclosed