Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL235678 | 0.78 | — | — | |
| SCHEMBL6178791 | 0.78 | TSHR (0.43) | ALDH1A1TSHRTDP1 | |
| SCHEMBL9036085 | 0.76 | — | — | |
| SCHEMBL10447818 | 0.70 | TSHR (0.41) | ALDH1A1TSHRTDP1 | |
| SCHEMBL3146943 | 0.69 | — | — | |
| SCHEMBL22641704 | 0.69 | TSHR (0.45) | ALDH1A1TSHRTDP1 | |
| SCHEMBL12918357 | 0.68 | TSHR (0.46) | ALDH1A1TSHRTDP1 | |
| SCHEMBL5961122 | 0.68 | TSHR (0.39) | ALDH1A1TSHRTDP1 | |
| SCHEMBL13174761 | 0.67 | — | — | |
| SCHEMBL5932196 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110810-A1 | PYRAZOLE AMIDE DERIVATIVE | Teijin Pharma Limited (JP) | 2017-01-04 | — | — | EP | disclosed |
| WO-2015129926-A1 | PYRAZOLE AMIDE DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2015-09-03 | — | — | WO | disclosed |