⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57503 | 1.00 | — | — | |
| SCHEMBL25983900 | 0.87 | TSHR (0.39) | — | |
| SCHEMBL11115038 | 0.85 | TSHR (0.37) | — | |
| SCHEMBL87843 | 0.84 | — | — | |
| Ethylene SCHEMBL21634076 | 0.82 | TSHR (0.40) | — | |
| SCHEMBL564664 | 0.82 | TSHR (0.42) | — | |
| SCHEMBL28096163 | 0.82 | TSHR (0.35) | — | |
| SCHEMBL25172364 | 0.80 | TSHR (0.46) | — | |
| SCHEMBL632478 | 0.80 | TSHR (0.46) | — | |
| SCHEMBL9773418 | 0.80 | TSHR (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3133747-A1 | METHOD AND APPARATUS FOR TRANSMITTING AND FEEDING BACK SIGNAL | Huawei Technologies Co., Ltd. (CN) | 2017-02-22 | — | — | EP | disclosed |
| EP-3110429-A1 | ADOPTIVE CELLULAR THERAPY USING AN AGONIST OF RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR GAMMA & RELATED THERAPEUTIC METHODS | Lycera Corporation (US) | 2017-01-04 | — | — | EP | disclosed |
| WO-2015131035-A1 | ADOPTIVE CELLULAR THERAPY USING AN AGONIST OF RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR GAMMA & RELATED THERAPEUTIC METHODS | LYCERA CORPORATION (US) | 2015-09-03 | — | — | WO | disclosed |