Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17049468 | 1.00 | CNR1 (0.42) | CNR1CNR2ATMALDH1A1LMNA | |
| SCHEMBL2763063 | 1.00 | CNR1 (0.42) | CNR1CNR2ATMALDH1A1LMNA | |
| SCHEMBL2623657 | 1.00 | CNR1 (0.42) | CNR1CNR2ATMALDH1A1LMNA | |
| SCHEMBL2763061 | 1.00 | CNR1 (0.42) | CNR1CNR2ATMALDH1A1LMNA | |
| SCHEMBL17049473 | 0.91 | MAOB (0.40) | CNR1CNR2ATMALDH1A1LMNA | |
| SCHEMBL13376358 | 0.87 | MAP4K4 (0.41) | ATMALDH1A1LMNASMN1; SMN2MAP4K4 | |
| SCHEMBL20810492 | 0.87 | HPGD (0.42) | ATMALDH1A1LMNASMN1; SMN2MAP4K4 | |
| SCHEMBL2764163 | 0.87 | CNR2 (0.48) | CNR1CNR2ATMALDH1A1LMNA | |
| SCHEMBL13302517 | 0.87 | CNR2 (0.48) | CNR1CNR2ATMALDH1A1LMNA | |
| SCHEMBL2764166 | 0.87 | CNR2 (0.48) | CNR1CNR2ATMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120723-B2 | Modulator | CANBEX THERAPEUTICS LIMITED (GB) | 2015-09-01 | — | — | US | disclosed |
| US-9120723-B2 | Modulator | CANBEX THERAPEUTICS LIMITED (GB) | 2015-09-01 | — | — | US | disclosed |