Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 16/20 | 0.72 |
| ▸ | FLT4 | P35916 | 11/20 | 0.72 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12479644 | 0.99 | PTK2 (0.71) | PTK2FLT4ALK | |
| SCHEMBL14635976 | 0.95 | PTK2 (0.72) | PTK2FLT4ALK | |
| SCHEMBL12479555 | 0.94 | PTK2 (0.82) | PTK2FLT4ALK | |
| Lithium Ion SCHEMBL12479642 | 0.93 | PTK2 (0.71) | PTK2FLT4ALK | |
| Acetic Acid SCHEMBL27949192 | 0.91 | PTK2 (0.65) | PTK2FLT4ALK | |
| SCHEMBL14617553 | 0.89 | PTK2 (0.71) | PTK2FLT4 | |
| SCHEMBL14648864 | 0.89 | PTK2 (0.83) | PTK2FLT4 | |
| SCHEMBL14648384 | 0.88 | PTK2 (0.69) | PTK2FLT4 | |
| SCHEMBL12478760 | 0.88 | PTK2 (0.70) | PTK2FLT4 | |
| SCHEMBL14635374 | 0.88 | PTK2 (0.70) | PTK2FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9174946-B2 | Selective FAK inhibitors | CANCER THERAPEUTICS CRC PTY LTD (AU) | 2015-11-03 | — | — | US | disclosed |
| US-9120761-B2 | Selective FAK inhibitors | CANCER THERAPEUTICS CRC PTY LTD (AU) | 2015-09-01 | — | — | US | disclosed |