Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1958169 | 0.93 | BCL2 (0.62) | BCL2 | |
| SCHEMBL19424690 | 0.91 | — | — | |
| SCHEMBL1959769 | 0.90 | BCL2 (0.72) | BCL2 | |
| SCHEMBL19410469 | 0.88 | BCL2 (0.57) | BCL2 | |
| SCHEMBL19424855 | 0.85 | — | — | |
| SCHEMBL1957126 | 0.84 | BCL2 (0.59) | BCL2 | |
| SCHEMBL2996436 | 0.83 | BCL2 (0.74) | BCL2 | |
| SCHEMBL19424630 | 0.83 | — | — | |
| SCHEMBL1955752 | 0.83 | BCL2 (0.76) | BCL2 | |
| SCHEMBL1958976 | 0.82 | BCL2 (0.64) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9125913-B2 | Bcl-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases | ABBVIE INC. (US) | 2015-09-08 | — | — | US | claimed |