Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 3/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17054148 | 0.95 | BCL2 (0.75) | BCL2 | |
| SCHEMBL1958112 | 0.90 | BCL2 (0.88) | BCL2 | |
| SCHEMBL1957435 | 0.89 | BCL2 (0.87) | BCL2 | |
| SCHEMBL1957488 | 0.89 | BCL2 (0.76) | BCL2 | |
| SCHEMBL1960251 | 0.88 | BCL2 (0.85) | BCL2 | |
| SCHEMBL1957817 | 0.87 | BCL2 (0.91) | BCL2 | |
| SCHEMBL1955089 | 0.87 | BCL2 (0.87) | BCL2 | |
| SCHEMBL1956290 | 0.87 | BCL2 (0.87) | BCL2 | |
| SCHEMBL1958236 | 0.86 | BCL2 (0.88) | BCL2 | |
| SCHEMBL17054149 | 0.86 | BCL2 (0.73) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9125913-B2 | Bcl-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases | ABBVIE INC. (US) | 2015-09-08 | — | — | US | claimed |