SCHEMBL17059116

SCHEMBL17059116

C=CCCCCn1c(=O)n(CCCCC=C)n(CCCCC=C)c1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.39
TSHR P16473 3/20 0.37
ALDH1A1 P00352 3/20 0.37
NPSR1 Q6W5P4 1/20 0.36
ABCC4 O15439 1/20 0.34
MAPT P10636 1/20 0.34
USP2 O75604 1/20 0.33
LMNA P02545 2/20 0.32
GALR3 O60755 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ADORA2B P29275 2/20 0.32
PDE4A P27815 1/20 0.32
ADORA2A P29274 1/20 0.32
PDE4B Q07343 1/20 0.32
PDE4C Q08493 1/20 0.32
PDE4D Q08499 1/20 0.32
ADORA1 P30542 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17059126 0.93 CYP3A4 (0.41) CYP3A4TSHRALDH1A1NPSR1ABCC4
SCHEMBL13835669 0.91 CYP3A4 (0.48) CYP3A4TSHRALDH1A1NPSR1ABCC4
SCHEMBL17041949 0.89 CYP3A4 (0.46) CYP3A4TSHRALDH1A1NPSR1ABCC4
SCHEMBL20495994 0.89 CYP3A4 (0.46) CYP3A4TSHRALDH1A1NPSR1ABCC4
SCHEMBL20495993 0.89 CYP3A4 (0.46) CYP3A4TSHRALDH1A1NPSR1ABCC4
SCHEMBL17059118 0.87 CYP3A4 (0.39) CYP3A4TSHRALDH1A1NPSR1ABCC4
SCHEMBL17059124 0.85 CYP3A4 (0.43) CYP3A4TSHRALDH1A1NPSR1ABCC4
SCHEMBL9998956 0.84 CYP3A4 (0.50) CYP3A4TSHRALDH1A1NPSR1ABCC4
SCHEMBL19407022 0.82 TSHR (0.56) CYP3A4TSHRALDH1A1LMNAGALR3
SCHEMBL19155603 0.80 CYP3A4 (0.46) CYP3A4TSHRALDH1A1NPSR1ABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2913331-A1 METHOD FOR PRODUCING EPOXY COMPOUND Nissan Chemical Industries, Ltd. (JP) 2015-09-02 EP disclosed