Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 7/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.50 |
| ▸ | GAK | O14976 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | CBFB | Q13951 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16289148 | 0.81 | RIPK2 (0.58) | RIPK2KDRRETMAPK14PKMYT1 | |
| SCHEMBL30880575 | 0.80 | RIPK2 (0.50) | RIPK2KDRRETMAPK14PKMYT1 | |
| SCHEMBL2588818 | 0.80 | NR4A2 (0.53) | RIPK2KDRRETMAPK14PKMYT1 | |
| SCHEMBL601007 | 0.80 | RIPK2 (0.56) | RIPK2KDRRETMAPK14PKMYT1 | |
| SCHEMBL600488 | 0.80 | RIPK2 (0.50) | RIPK2KDRRETMAPK14PKMYT1 | |
| SCHEMBL16289146 | 0.80 | RIPK2 (0.50) | RIPK2KDRRETMAPK14PKMYT1 | |
| SCHEMBL14730905 | 0.80 | RIPK2 (0.47) | RIPK2KDRRETMAPK14PKMYT1 | |
| SCHEMBL26317970 | 0.79 | GAK (0.64) | RIPK2KDRRETMAPK14PKMYT1 | |
| SCHEMBL17059460 | 0.78 | RIPK2 (0.48) | RIPK2KDRRETMAPK14PKMYT1 | |
| SCHEMBL10106288 | 0.76 | PDE4B (0.44) | RIPK2KDRRETMAPK14PKMYT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566477-B1 | AMINO-QUINOLINES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2015-09-02 | — | — | EP | disclosed |