Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 1.00 |
| ▸ | BTK | Q06187 | 3/20 | 0.65 |
| ▸ | JAK3 | P52333 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17059690 | 0.92 | EGFR (1.00) | EGFRBTKJAK3 | |
| SCHEMBL17059701 | 0.90 | EGFR (0.82) | EGFRBTKJAK3 | |
| SCHEMBL17059659 | 0.90 | EGFR (0.87) | EGFRJAK3 | |
| SCHEMBL17059644 | 0.90 | EGFR (1.00) | EGFRBTKJAK3 | |
| SCHEMBL17059584 | 0.89 | EGFR (1.00) | EGFRJAK3 | |
| SCHEMBL17059606 | 0.88 | EGFR (1.00) | EGFRBTKJAK3 | |
| SCHEMBL17059651 | 0.88 | EGFR (0.78) | EGFRBTKJAK3 | |
| SCHEMBL17059704 | 0.88 | EGFR (0.85) | EGFRJAK3 | |
| SCHEMBL17059625 | 0.87 | EGFR (1.00) | EGFRJAK3 | |
| SCHEMBL17059700 | 0.86 | EGFR (0.76) | EGFRBTKJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015127873-A1 | ARYLAMINO PYRAMIDINE COMPOUND AND APPLICATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICALLY ACCEPTABLE COMPOSITIONS PREPARED THEREFROM | 上海海雁医药科技有限公司 | 2015-09-03 | — | — | WO | disclosed |