Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 4/20 | 0.60 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.45 |
| ▸ | SELE | P16581 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17059811 | 0.78 | USP7 (0.48) | USP7ICAM1SELERAB9ASMN1; SMN2 | |
| SCHEMBL2980445 | 0.78 | USP7 (0.56) | USP7ICAM1SELERAB9ASMN1; SMN2 | |
| SCHEMBL17059872 | 0.77 | USP7 (0.76) | USP7RAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL17059871 | 0.77 | USP7 (0.59) | USP7ICAM1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5168265 | 0.77 | USP7 (0.56) | USP7RAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL17059820 | 0.76 | USP7 (0.54) | USP7ICAM1SELERAB9ANPC1 | |
| SCHEMBL17059815 | 0.75 | USP7 (1.00) | USP7RAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL17059814 | 0.75 | EDNRA (0.47) | USP7RAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL17059817 | 0.74 | USP7 (0.49) | USP7ICAM1SELERAB9ASMN1; SMN2 | |
| SCHEMBL17059868 | 0.74 | USP7 (0.59) | USP7RAB9ASMN1; SMN2NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015127797-A1 | THIAZOLE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF IN PHARMACEUTICAL PRODUCTION | 中国药科大学 | 2015-09-03 | — | — | WO | disclosed |