Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK7 | Q13164 | 10/20 | 0.51 |
| ▸ | BRD4 | O60885 | 8/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.38 |
| ▸ | DCLK1 | O15075 | 4/20 | 0.38 |
| ▸ | NUAK1 | O60285 | 2/20 | 0.38 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18369796 | 0.83 | BRD4 (0.70) | MAPK7BRD4KCNH2NR1H2NR1H3 | |
| SCHEMBL17059911 | 0.76 | BRD4 (0.70) | MAPK7BRD4KCNH2NR1H2NR1H3 | |
| SCHEMBL18369881 | 0.75 | BRD4 (0.69) | MAPK7BRD4KCNH2LRRK2DCLK1 | |
| SCHEMBL18370096 | 0.75 | MAPK7 (0.48) | MAPK7BRD4KCNH2LRRK2DCLK1 | |
| SCHEMBL18379131 | 0.74 | BRD4 (0.68) | MAPK7BRD4KCNH2LRRK2DCLK1 | |
| SCHEMBL18369886 | 0.74 | MAPK7 (0.57) | MAPK7BRD4KCNH2LRRK2DCLK1 | |
| SCHEMBL18370084 | 0.74 | MAPK7 (0.51) | MAPK7BRD4KCNH2LRRK2DCLK1 | |
| SCHEMBL18369863 | 0.74 | MAPK7 (0.55) | MAPK7BRD4KCNH2NR1H2NR1H3 | |
| SCHEMBL18370089 | 0.74 | MAPK7 (0.61) | MAPK7BRD4KCNH2LRRK2DCLK1 | |
| SCHEMBL18370088 | 0.74 | BRD4 (0.60) | MAPK7BRD4KCNH2LRRK2DCLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015129927-A1 | HETEROCYCLIC COMPOUNDS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2015-09-03 | — | — | WO | disclosed |