Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 14/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 8/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.42 |
| ▸ | CCR4 | P51679 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707011 | 0.90 | CCR6 (0.48) | CCR6CXCR2CXCR1CXCR3CCR4 | |
| SCHEMBL1705931 | 0.84 | CXCR2 (0.62) | CCR6CXCR2CXCR1CXCR3CCR4 | |
| SCHEMBL1705853 | 0.81 | CCR6 (0.52) | CCR6CXCR2CXCR1CXCR3CCR4 | |
| SCHEMBL1707138 | 0.79 | CCR6 (0.59) | CCR6 | |
| SCHEMBL1706970 | 0.78 | CCR6 (0.44) | CCR6CXCR2CXCR1CXCR3CCR4 | |
| SCHEMBL1705963 | 0.76 | CCR6 (0.76) | CCR6 | |
| SCHEMBL12385977 | 0.75 | CCR6 (0.63) | CCR6CXCR2 | |
| SCHEMBL1579831 | 0.75 | CCR6 (0.63) | CCR6CXCR2 | |
| SCHEMBL1579827 | 0.75 | CCR6 (0.63) | CCR6CXCR2 | |
| SCHEMBL5711827 | 0.74 | CXCR2 (0.52) | CCR6CXCR2CXCR1CXCR3CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155670-B1 | ANTI -INFLAMMATORY SUBSTITUTED CYCLOBUTENEDIONE COMPOUNDS | NOVARTIS AG (CH) | 2012-04-18 | — | — | EP | claimed |