Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 20/20 | 0.84 |
| ▸ | DYRK1B | Q9Y463 | 8/20 | 0.75 |
| ▸ | GSK3A | P49840 | 1/20 | 0.75 |
| ▸ | GSK3B | P49841 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17060624 | 0.91 | DYRK1A (1.00) | DYRK1ADYRK1BGSK3AGSK3B | |
| SCHEMBL14733551 | 0.91 | DYRK1A (1.00) | DYRK1ADYRK1BGSK3AGSK3B | |
| SCHEMBL14733564 | 0.89 | DYRK1A (1.00) | DYRK1ADYRK1BGSK3AGSK3B | |
| SCHEMBL16075927 | 0.86 | DYRK1A (1.00) | DYRK1ADYRK1BGSK3AGSK3B | |
| SCHEMBL14733533 | 0.85 | DYRK1A (1.00) | DYRK1ADYRK1BGSK3AGSK3B | |
| SCHEMBL17060605 | 0.85 | DYRK1A (0.89) | DYRK1ADYRK1BGSK3AGSK3B | |
| SCHEMBL14733514 | 0.82 | DYRK1A (1.00) | DYRK1ADYRK1BGSK3AGSK3B | |
| SCHEMBL16039180 | 0.82 | DYRK1A (0.83) | DYRK1ADYRK1BGSK3AGSK3B | |
| SCHEMBL14733524 | 0.82 | DYRK1A (0.75) | DYRK1ADYRK1BGSK3AGSK3B | |
| SCHEMBL14733488 | 0.82 | DYRK1A (0.68) | DYRK1ADYRK1BGSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2744797-B1 | DYRK1 INHIBITORS AND USES THEREOF | DIAXONHIT (FR) | 2015-09-09 | — | — | EP | claimed |