SCHEMBL17060764

SCHEMBL17060764

COC(=O)[C@H](Cc1ccc(-c2ccc(C#N)cc2)cc1)NC(=O)C1Cc2cc3c(cc2CN1C(=O)O)O[C@@H](c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1)CN3C(C)=O

nearest known ligand 0.82

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 20/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2020544 0.94 GLP1R (0.77) GLP1R
SCHEMBL2020545 0.94 GLP1R (0.77) GLP1R
SCHEMBL2021616 0.90 GLP1R (1.00) GLP1R
SCHEMBL2021615 0.90 GLP1R (1.00) GLP1R
SCHEMBL2021613 0.90 GLP1R (1.00) GLP1R
SCHEMBL2021610 0.90 GLP1R (1.00) GLP1R
SCHEMBL12574079 0.90 GLP1R (1.00) GLP1R
SCHEMBL17060782 0.89 GLP1R (0.77) GLP1R
SCHEMBL539799 0.88 GLP1R (0.69) GLP1R
SCHEMBL539800 0.88 GLP1R (0.69) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2413693-B1 SUBSTITUTED AZOANTHRACENE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF VTV THERAPEUTICS LLC (US) 2015-09-09 EP disclosed