⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3302483 | 0.97 | — | — | |
| SCHEMBL3291670 | 0.92 | — | — | |
| SCHEMBL29311950 | 0.90 | SOAT1 (0.43) | — | |
| SCHEMBL11171034 | 0.90 | SOAT1 (0.43) | — | |
| SCHEMBL1478263 | 0.86 | — | — | |
| SCHEMBL25273914 | 0.79 | FOLH1 (0.36) | — | |
| SCHEMBL13374708 | 0.79 | RECQL (0.42) | — | |
| SCHEMBL154914 | 0.78 | — | — | |
| SCHEMBL2625079 | 0.78 | — | — | |
| SCHEMBL3078846 | 0.77 | TSHR (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012031298-A2 | ETHYNYLBENZENE DERIVATIVES | DUKE UNIVERSITY (US) | 2012-03-08 | — | — | WO | claimed |
| EP-1341755-A1 | CARBOXYLIC ACID AMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOEMBOLIC DISEASES AND TUMOURS | MERCK PATENT GmbH (DE) | 2003-09-10 | — | — | EP | claimed |
| EP-0874846-B1 | PURINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | NOVARTIS AG (CH) | 2003-04-02 | — | — | EP | claimed |
| WO-2002048099-A1 | CARBOXYLIC ACID AMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOEMBOLIC DISEASES AND TUMOURS | MERCK PATENT GMBH (DE) | 2002-06-20 | — | — | WO | claimed |
| EP-0972066-A1 | ENZYMATIC CONVERSION OF $g(a)-HYDROXYNITRILES TO THE CORRESPONDING $g(a)-HYDROXYAMIDES, ACIDS OR ACID SALTS | Novus International, Inc. (US) | 2000-01-19 | — | — | EP | claimed |
| WO-1998050031-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-11-12 | — | — | WO | claimed |
| EP-0874846-A1 | PURINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | Novartis AG (CH) | 1998-11-04 | — | — | EP | claimed |
| WO-1998032872-A1 | ENZYMATIC CONVERSION OF α-HYDROXYNITRILES TO THE CORRESPONDING α-HYDROXYAMIDES, ACIDS OR ACID SALTS | NOVUS INTERNATIONAL, INC. (US) | 1998-07-30 | — | — | WO | claimed |
| WO-1997016452-A1 | PURINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | NOVARTIS AG (CH) | 1997-05-09 | — | — | WO | claimed |
| EP-0577473-B1 | Reducing cosmetic composition for the permanent deformation of hair based on a mercaptoalkylamino-amide and process for the permanent deformation of hair | OREAL (FR) | 1995-12-20 | — | — | EP | claimed |
| EP-0577473-A1 | Reducing cosmetic composition for the permanent deformation of hair based on a mercaptoalkylamino-amide and process for the permanent deformation of hair | L'OREAL (FR) | 1994-01-05 | — | — | EP | claimed |
| US-4545985-A | ANTICARCINOGENIC AGENTS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 1985-10-08 | — | — | US | claimed |
| EP-0057140-B1 | THIOLATED POLYPEPTIDIC COMPOUND FROM A TETANIC TOXIN FRAGMENT, PROCESS FOR ITS PRODUCTION AND ITS APPLICATIONS | INSTITUT PASTEUR (FR) | 1985-07-17 | — | — | EP | claimed |
| EP-0030496-B1 | THIOLATED POLYPEPTIDIC COMPOUND COMING FROM A FRAGMENT OF TETANIC TOXINE, PROCESS FOR OBTAINING IT AND ITS APPLICATIONS | INSTITUT PASTEUR (FR) | 1983-07-13 | — | — | EP | claimed |
| EP-0057140-A2 | Thiolated polypeptidic compound from a tetanic toxin fragment, process for its production and its applications | INSTITUT PASTEUR (FR) | 1982-08-04 | — | — | EP | claimed |
| EP-0030496-A1 | Thiolated polypeptidic compound coming from a fragment of tetanic toxine, process for obtaining it and its applications | INSTITUT PASTEUR (FR) | 1981-06-17 | — | — | EP | claimed |
| US-20240358710-A1 | METHODS, COMPOSITIONS AND DEVICES FOR TREATING CANCER WITH ILLUDOFULVENES | AF CHEMICALS, LLC (US) | 2024-10-31 | — | — | US | disclosed |
| US-12023339-B2 | Methods, compositions and devices for treating cancer with illudofulvenes | AF CHEMICALS, LLC (US) | 2024-07-02 | — | — | US | disclosed |
| EP-0057140-A2 | Thiolated polypeptidic compound from a tetanic toxin fragment, process for its production and its applications | INSTITUT PASTEUR (FR) | 1982-08-04 | — | — | EP | disclosed |
| EP-0030496-A1 | Thiolated polypeptidic compound coming from a fragment of tetanic toxine, process for obtaining it and its applications | INSTITUT PASTEUR (FR) | 1981-06-17 | — | — | EP | disclosed |