Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77101 | 1.00 | — | — | |
| SCHEMBL5387 | 1.00 | — | — | |
| SCHEMBL4822887 | 0.97 | MEN1 (0.38) | MEN1KMT2ACHRNA7CYP2D6CYP19A1 | |
| Hydrochloric Acid SCHEMBL522550 | 0.97 | MEN1 (0.38) | MEN1KMT2ACHRNA7CYP2D6CYP19A1 | |
| Piperazine SCHEMBL28179364 | 0.97 | MEN1 (0.38) | MEN1KMT2ACHRNA7CYP2D6CYP19A1 | |
| SCHEMBL12403231 | 0.97 | MEN1 (0.38) | MEN1KMT2ACHRNA7CYP2D6CYP19A1 | |
| SCHEMBL13509549 | 0.97 | MEN1 (0.38) | MEN1KMT2ACHRNA7CYP2D6CYP19A1 | |
| Iodide SCHEMBL30375035 | 0.97 | MEN1 (0.38) | MEN1KMT2ACHRNA7CYP2D6CYP19A1 | |
| Hydrochloric Acid SCHEMBL1742546 | 0.97 | MEN1 (0.38) | MEN1KMT2ACHRNA7CYP2D6CYP19A1 | |
| SCHEMBL26646493 | 0.97 | MEN1 (0.38) | MEN1KMT2ACHRNA7CYP2D6CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195307-B1 | PIPERAZINE DERIVATIVE HAVING AFFINITY FOR THE HISTAMINE H3 RECEPTOR | GLAXO GROUP LTD (GB) | 2012-04-18 | — | — | EP | disclosed |