Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 18/20 | 0.79 |
| ▸ | EGFR | P00533 | 7/20 | 0.79 |
| ▸ | TEC | P42680 | 4/20 | 0.77 |
| ▸ | BMX | P51813 | 4/20 | 0.77 |
| ▸ | LYN | P07948 | 3/20 | 0.77 |
| ▸ | ITK | Q08881 | 3/20 | 0.77 |
| ▸ | TXK | P42681 | 2/20 | 0.77 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.77 |
| ▸ | ABL1 | P00519 | 2/20 | 0.77 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.77 |
| ▸ | LCK | P06239 | 2/20 | 0.77 |
| ▸ | FYN | P06241 | 2/20 | 0.77 |
| ▸ | YES1 | P07947 | 2/20 | 0.77 |
| ▸ | HCK | P08631 | 2/20 | 0.77 |
| ▸ | FGR | P09769 | 2/20 | 0.77 |
| ▸ | SRC | P12931 | 2/20 | 0.77 |
| ▸ | FER | P16591 | 2/20 | 0.77 |
| ▸ | CSK | P41240 | 2/20 | 0.77 |
| ▸ | BLK | P51451 | 2/20 | 0.77 |
| ▸ | JAK3 | P52333 | 2/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18335270 | 0.95 | BTK (0.77) | BTKEGFRTECBMXLYN | |
| SCHEMBL18335275 | 0.94 | BTK (0.86) | BTKEGFRTECBMXLYN | |
| SCHEMBL17065612 | 0.92 | BTK (0.68) | BTKEGFRTECBMXLYN | |
| SCHEMBL17065625 | 0.92 | BTK (0.72) | BTKEGFRTECBMXLYN | |
| SCHEMBL17065747 | 0.90 | BTK (0.71) | BTKEGFRTECBMXLYN | |
| SCHEMBL31279081 | 0.90 | BTK (0.79) | BTKEGFRTECBMXLYN | |
| SCHEMBL18335312 | 0.89 | BTK (0.73) | BTKEGFRTECBMXLYN | |
| SCHEMBL18335314 | 0.89 | BTK (0.75) | BTKEGFRTECBMXLYN | |
| SCHEMBL17065681 | 0.88 | ITK (0.67) | BTKEGFRTECBMXLYN | |
| SCHEMBL19176244 | 0.88 | BTK (0.71) | BTKEGFRTECBMXLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102579-B1 | HETEROCYCLIC COMPOUNDS | CADILA HEALTHCARE LTD (IN) | 2019-04-10 | — | — | EP | claimed |
| US-9840509-B2 | Heterocyclic compounds | CADILA HEALTHCARE LIMITED (IN) | 2017-12-12 | — | — | US | claimed |
| US-20160376277-A1 | NOVEL HETEROCYCLIC COMPOUNDS | CADILA HEALTHCARE LIMITED (IN) | 2016-12-29 | — | — | US | claimed |
| EP-3102579-A2 | HETEROCYCLIC COMPOUNDS | Cadila Healthcare Limited (IN) | 2016-12-14 | — | — | EP | claimed |
| WO-2015132799-A2 | NOVEL HETEROCYCLIC COMPOUNDS | CADILA HEALTHCARE LIMITED (IN) | 2015-09-11 | — | — | WO | claimed |
| EP-3102579-B1 | HETEROCYCLIC COMPOUNDS | CADILA HEALTHCARE LTD (IN) | 2019-04-10 | — | — | EP | disclosed |
| US-9840509-B2 | Heterocyclic compounds | CADILA HEALTHCARE LIMITED (IN) | 2017-12-12 | — | — | US | disclosed |
| US-9840509-B2 | Heterocyclic compounds | CADILA HEALTHCARE LIMITED (IN) | 2017-12-12 | — | — | US | disclosed |
| US-9840509-B2 | Heterocyclic compounds | CADILA HEALTHCARE LIMITED (IN) | 2017-12-12 | — | — | US | disclosed |
| US-20160376277-A1 | NOVEL HETEROCYCLIC COMPOUNDS | CADILA HEALTHCARE LIMITED (IN) | 2016-12-29 | — | — | US | disclosed |
| US-20160376277-A1 | NOVEL HETEROCYCLIC COMPOUNDS | CADILA HEALTHCARE LIMITED (IN) | 2016-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160376277-A1 | NOVEL HETEROCYCLIC COMPOUNDS | BTK, LYN, SYK | BTK 1/4885EGFR 425/4885TEC 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.