Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 17/20 | 0.83 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | GSK3A | P49840 | 2/20 | 0.54 |
| ▸ | GSK3B | P49841 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13435537 | 0.91 | QPCT (1.00) | QPCT | |
| SCHEMBL1706070 | 0.90 | QPCT (0.83) | QPCTNPC1RAB9AL3MBTL1 | |
| SCHEMBL16948533 | 0.89 | QPCT (0.69) | QPCTNPC1RAB9AGSK3AGSK3B | |
| SCHEMBL1706008 | 0.88 | QPCT (0.84) | QPCTGSK3AGSK3BALDH1A1HTT | |
| SCHEMBL1706795 | 0.88 | QPCT (0.67) | QPCT | |
| SCHEMBL1706589 | 0.88 | QPCT (0.84) | QPCTGSK3BMAPK1HTT | |
| SCHEMBL1706314 | 0.87 | QPCT (0.85) | QPCTNPC1RAB9AALDH1A1HTT | |
| SCHEMBL1706435 | 0.85 | QPCT (0.85) | QPCT | |
| SCHEMBL1706173 | 0.84 | QPCT (0.84) | QPCT | |
| SCHEMBL1706075 | 0.83 | QPCT (0.85) | QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091948-B1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2012-04-18 | — | — | EP | claimed |