Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.40 |
| ▸ | HTR2C | P28335 | 5/20 | 0.40 |
| ▸ | HTR2B | P41595 | 5/20 | 0.40 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.35 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.35 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.35 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | CACNA1E | Q15878 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17055180 | 0.91 | CACNB4 (0.40) | HTR2AHTR2CHTR2BCACNB4CACNA1A | |
| SCHEMBL17055179 | 0.79 | CACNB4 (0.40) | HTR2AHTR2CHTR2BCACNB4CACNA1A | |
| SCHEMBL17066195 | 0.73 | HTR2C (0.44) | HTR2AHTR2CHTR2B | |
| SCHEMBL17066443 | 0.67 | HTR2A (0.38) | HTR2AHTR2CHTR2BCACNB4CACNA1A | |
| SCHEMBL18250386 | 0.65 | HTR2A (0.37) | HTR2AHTR2CHTR2BCACNB4CACNA1A | |
| SCHEMBL18237855 | 0.64 | SLC6A4 (0.43) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL24245094 | 0.63 | HTR2C (0.60) | HTR2AHTR2CHTR2BPBRM1LDHA | |
| SCHEMBL11292597 | 0.63 | HTR2C (0.46) | HTR2AHTR2CHTR2BHRH3MEN1 | |
| SCHEMBL18250387 | 0.63 | HTR2A (0.35) | HTR2AHTR2CHTR2BCACNB4CACNA1A | |
| SCHEMBL16961515 | 0.63 | HTR2C (0.50) | HTR2AHTR2CHTR2BPBRM1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9125866-B1 | Antidepressant compounds | KING SAUD UNIVERSITY (SA) | 2015-09-08 | — | — | US | disclosed |