Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16775667 | 0.93 | ALK (0.65) | ALK | |
| SCHEMBL897014 | 0.93 | ALK (0.65) | ALK | |
| SCHEMBL897780 | 0.88 | ALK (0.78) | ALK | |
| SCHEMBL898563 | 0.88 | ALK (0.78) | ALK | |
| SCHEMBL16775684 | 0.88 | ALK (0.64) | ALK | |
| SCHEMBL897777 | 0.88 | ALK (0.78) | ALK | |
| SCHEMBL897839 | 0.88 | ALK (0.64) | ALK | |
| SCHEMBL897838 | 0.88 | ALK (0.64) | ALK | |
| SCHEMBL898031 | 0.88 | ALK (0.64) | ALK | |
| SCHEMBL897778 | 0.88 | ALK (0.78) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9126931-B2 | Tetracyclic compound | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2015-09-08 | — | — | US | disclosed |