Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.78 |
| ▸ | MEN1 | O00255 | 5/20 | 0.78 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | AKT1 | P31749 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13453476 | 0.89 | KMT2A (0.82) | KMT2AMEN1ALOX12GAAALDH1A1 | |
| SCHEMBL17066499 | 0.89 | KMT2A (0.81) | KMT2AMEN1ALOX12GAAALDH1A1 | |
| SCHEMBL13469714 | 0.88 | KMT2A (0.86) | KMT2AMEN1ALOX12GAAALDH1A1 | |
| SCHEMBL13453473 | 0.88 | KMT2A (0.86) | KMT2AMEN1ALOX12GAAALDH1A1 | |
| SCHEMBL13470358 | 0.88 | KMT2A (1.00) | KMT2AMEN1ALOX12GAAALDH1A1 | |
| SCHEMBL17066589 | 0.88 | KMT2A (0.86) | KMT2AMEN1ALOX12GAAALDH1A1 | |
| SCHEMBL13453522 | 0.88 | KMT2A (0.86) | KMT2AMEN1ALOX12GAAALDH1A1 | |
| SCHEMBL17066495 | 0.87 | KMT2A (0.85) | KMT2AMEN1ALOX12GAAALDH1A1 | |
| SCHEMBL13469940 | 0.87 | KMT2A (0.79) | KMT2AMEN1ALOX12GAAALDH1A1 | |
| SCHEMBL13453543 | 0.87 | KMT2A (0.85) | KMT2AMEN1ALOX12GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9126938-B2 | Phosphatidylcholine transfer protein inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2015-09-08 | — | — | US | disclosed |