Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17066723 | 1.00 | CYP2A6 (0.55) | CYP2A6MAPTMEN1LMNACYP1A2 | |
| SCHEMBL15747113 | 0.98 | CYP2A6 (0.56) | CYP2A6MAPTMEN1LMNACYP1A2 | |
| SCHEMBL14985690 | 0.87 | CYP2A6 (0.47) | CYP2A6MAPTMEN1LMNACYP1A2 | |
| SCHEMBL7483325 | 0.82 | CYP2A6 (0.53) | CYP2A6MAPTCDK5GSK3BCCNB2 | |
| SCHEMBL17533003 | 0.82 | CYP2A6 (0.53) | CYP2A6MAPTMEN1LMNACYP1A2 | |
| SCHEMBL24427567 | 0.82 | CYP2A6 (0.53) | CYP2A6MAPTMEN1CYP3A4KMT2A | |
| SCHEMBL9668668 | 0.82 | CYP2A6 (0.53) | CYP2A6MAPTMEN1KMT2ACDK5 | |
| SCHEMBL7904690 | 0.82 | POLB (0.61) | CYP2A6MAPTCCNB2CDK1CCNB1 | |
| SCHEMBL28559389 | 0.82 | CYP2A6 (0.53) | CYP2A6MEN1KMT2ASMPD3CDK5 | |
| SCHEMBL5292919 | 0.81 | CYP2A6 (0.67) | CYP2A6SMPD3CDK5CCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9125904-B1 | Biphenyl imidazoles and related compounds useful for treating HCV infections | ACHILLION PHARMACEUTICALS, INC. (US) | 2015-09-08 | — | — | US | disclosed |